The BBSRC National Vaccinology Centre: The Jenner Building

Submitted by louise_barton on Mon, 07/22/2019 - 11:59

The BBSRC National Vaccinology Centre accommodates in vitro research and supports in vivo research activities, primarily performed by the avian viral disease researchers, in addition to those research activities which do not require the high level of containment that the BBSRC National Virology Centre: The Plowright Building provides. The purpose of this facility is to provide low containment experimental facilities to support, enhance and extend the range of viruses studied at Pirbright and which provide specific disciplines (e.g. host genetics and genomics) in close proximity to both high and low containment experimental facilities. This capability is nationally unique because it supports studies of viruses not replicated elsewhere in the UK and because of its position in close proximity to High Containment Experimental Facilities in Pirbright. The BBSRC National Centre for Vaccinology expands capacity in a range of disciplines that enhance high containment studies (e.g. host genetics, genomics and immunology). This facility houses a wide range of groups working on strategically important endemic and exotic viral pathogens that can be handled under low containment including Marek’s disease virus, infectious bronchitis virus and low pathogenicity animal influenzas. Our in vivo facilities supporting avian research are housed in a separate facility. This enables study of internationally important avian viruses within the natural host. The high level objectives of this National Capability are to: support and enable high-quality research requiring low containment facilities and associated resources and expertise. This research includes: Science conducted as part of Pirbright’s two ISPs, other external funding from BBSRC and other sources (e.g. Defra, EU, Wellcome and others), collaborations with industry (including vaccine efficacy testing), sustain Pirbright’s global leadership of avian virus research and maintain and develop critical mass in this area; secure the UK’s ability to respond to outbreaks of avian diseases. The community interest in viruses of poultry is high, a consequence of a global population of over 50 billion chickens that form a significant component of food security. The application of genomic and host immunological analyses also adds a further dimension to studies both in high and low containment that is not currently replicated elsewhere in the UK for the viruses of interest.


Biological Sciences, Health & Food



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