The Centre for Preclinical Imaging aims to develop cutting-edge non-invasive imaging methods for assessing pathologies and response to treatment in the live animal. It aims to provide the expertise and infrastructure for non-invasive imaging in pre-clinical models to the research community at the University of Liverpool and its academic and industrial partners in the vicinity. The centre has been funded in large part by capital award funds from the MRC (£3.3M) and the UKRMP to establish the Safety and Efficacy Hub, Focusing on Imaging Technologies (£4.5M). The technologies available for pre-clinical imaging currently at the Centre include high-field magnetic resonance imaging (MRI), optical imaging, photo-acoustic imaging and ultrasound and will soon expand to include computed tomography (CT), single photon emission computed tomography (SPECT) and positron emission tomography (PET). These technologies enable non-invasive assessment of anatomy and function (MRI, CT, PET), metabolism (MRI, PET), protein expression and reporter gene expression (optical imaging, SPECT, PET), measurement of blood flow and vascularity (ultrasound, MRI, CT) and renal function (photo-acoustics, MRI) and have widespread applications for diagnostics and therapeutic interventions in neurology, neurosurgery, oncology, physiology, musculoskeletal biology and other relevant fields.
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