The biological mass spectrometry suite provides analytical expertise and practical support for academic (internal and external) and industrially funded research using high-end advanced analytical instrumentation. The facility has a range of liquid and gas chromatographs hyphenated with various mass spectrometers (LCMS and GCMS). Each instrument is dedicated to either proteomics (targeted, shotgun and non-labelled quantitation) or metabolomics (targeted/ untargeted metabolite profiling...

The Biomedical Imaging Unit is a joint University of Southampton (UoS)/ University Hospitals Southampton NHS Foundation Trust (UHS) facility for diagnostic and research microscopy. The BIU houses microscopes capable of 2-, 3- and 4D imaging (from brightfield microscopy through to confocal, light sheet, time lapse, virtual scanning, µCT, SEM, TEM & serial block face SEM) using a range of imaging sources (light, x-ray and electron). We are the only joint NHS/University imaging facility in the...

Biometrology - measuring biological systems to support the development of new bioproducts and services

NPL, as the UK's National Measurement Institute, is the prime deliverer of the UK Measurement Strategy. NPL is a world-leading centre of excellence in developing and applying the most accurate measurement standards, science and technology available. For more than a century, NPL has developed and maintained the nation's primary measurement standards. These standards underpin an...

The NMR facility provides research infrastructure and expertise primarily for projects related to biomacromolecules and their binding partners. Mostly supporting the various users from the Departments across the University, the facility is also open to external users from academia and industry. The majority of the work in the facility is done on a collaborative basis and support is adjusted according to the requirements of the users. The facility has three spectrometers that are operating at 800...

What it does: BioPilotsUK is a distributed infrastructure providing access to key hardware, skills and knowhow, for both industrial and academic R&D to aid innovation and de-risk the development of bio-based products and processes. Research Goals etc: • Provide simple-to-access responsive support to academia and businesses to accelerate innovative growth in the UK bioeconomy. • To assist UK industry realise potential investments in biobased research and innovation and bring new products to...

The Bioscience Technology Facility (BTF) provides access to technology and research services for the biosciences. This unique facility allows ready access to a wide range of technologies and expertise in an integrated manner that can help drive forward your research efficiently and cost effectively. The BTF is one coherent set of core labs which include Imaging and Cytometry, Genomics and Bioinformatics, Metabolomics and Proteomics, Molecular Interactions and Biophysics, and Protein Production...

Providing the research community with access to a range of resources for the genetic transformation of crops and genome editing; such as the development of new targeted gene knockout resources: CRISPR/Cas9 technology; Training facilities: hosting visitors for hands-on training at the John Innes Centre; Constructs: developed specifically for Brassica, Wheat and Barley - the pBRACT series of vectors

The ISMB Protein Crystallography & Biophysics (BiophysX) Centre provides coherent and supported access to a range of methodologies for the characterization and quantitative analysis of biomolecules and their interactions. The ISMB BiophysX Centre supports semi-automated screening of proteins and protein complexes for structural study including crystallization (robotic sample handling, Mosquito and crystal hotel system). We seek to enable accurate analysis of biomolecular interactions that...

The atmospheric concentration of carbon dioxide (CO2) is set to reach double pre-industrial levels by about 2050. This increase would be much faster were it not for the uptake of CO2 into the upper ocean and the terrestrial biosphere. Currently 2-3 of every 10 molecules of CO2 released by human activity is taken up into existing terrestrial ecosystems. The degree to which this uptake will continue as atmospheric CO2 concentrations increase, is not settled. Many of the most important processes...

The Bodleian Libraries mission is to provide an excellent service to support the learning, teaching and research objectives of the University of Oxford; and to develop and maintain access to Oxford's unique collections for the benefit of scholarship and society. The Bodleian has been collecting material for more than 400 years and currently holds more than 12 million printed items, over 80,000 e-journals, and some 56,000 linear metres of outstanding special collections. These include rare books...