ALSPAC is a multi-generational study that began as a pregnancy/birth cohort. In 1991 and 1992, 14,500 pregnant women living in and around Bristol were recruited into the study. Detailed data have been collected on these women and their partners (the original parents, known as G0) and their children (the index participants, G1). In recent years the study has also enrolled the children of the children (G2).

The overarching objective for ALSPAC is to maintain its position as the premier multi...

Hollin Hill Landslide Observatory, North Yorkshire At Hollin Hill a system of monitoring landslide movement has been developed by BGS by combining geomorphological mapping, terrestrial LiDAR and real-time monitoring with geophysics. Scientific research at this site has been designed to enable BGS to accurately monitor and eventually aid the forecasting of movement of the landslide. It brings together a combination of field surveying, geomorphological, geophysical, engineering and...

The Rock Mechanics and Physics Laboratory (RMPL) undertakes research on the physical properties and behaviour of rock specifically for: planning, design and construction within the civil engineering sector; extraction and storage within the energy sector; developing our understanding of near to surface to shallow crustal earth processes in order to help predict and mitigate the effects of small and large scale geohazards. The RMPL lab specialises in standard (ISRM and ASTM) and bespoke...

The University of Nottingham and University College London collaborate to lead the UK Clinical Research Collaboration (UKCRC) Tissue Directory and Coordination Centre, which is the UK's Node within BBMRI-ERIC. The Centre is led from the Advanced Data Analysis Centre at the University of Nottingham and supported by a team at UCL. It's work is guided by an Advisory Committee of external members from academia, industry, medical funding bodies, and regulatory agencies. The Centre supports the work...

UK Biobank is a major national and international health resource, and a registered charity in its own right, with the aim of improving the prevention, diagnosis and treatment of a wide range of serious and life-threatening illnesses to including cancer, heart diseases, stroke, diabetes, arthritis, osteoporosis, eye disorders, depression and forms of dementia. UK Biobank recruited 500,000 people aged between 40-69 years in 2006-2010 from across the country to take part in this project. They...

The National Biosample Centre Established by the NIHR in 2014, and operated by UK Biocentre as a not-for-profit organisation, we provide world leading sample management and high capacity bioprocessing. We make extensive use of dedicated automation and software systems for consistent and high throughput sample processing and tracking delivering best value for UK medical research. Our mission is to be the centre of excellence for UK sample management and a key part of the UK science...

The UK Biochar Research Centre (UKBRC) undertakes disciplinary and interdisciplinary research on: (1) Biochar production and analysis of energy rich co-products; (2) The diverse potential applications of biochar; particularly as a beneficial soil amendment, as well as other uses; (3) The feasible development of Pyrolysis-Biochar systems and Life Cycle Assessments for sustainable resource management. The facility contains four major instruments for the pyrolysis and characterisation of biochar...

The biological mass spectrometry suite provides analytical expertise and practical support for academic (internal and external) and industrially funded research using high-end advanced analytical instrumentation. The facility has a range of liquid and gas chromatographs hyphenated with various mass spectrometers (LCMS and GCMS). Each instrument is dedicated to either proteomics (targeted, shotgun and non-labelled quantitation) or metabolomics (targeted/ untargeted metabolite profiling...

The Biomedical Imaging Unit is a joint University of Southampton (UoS)/ University Hospitals Southampton NHS Foundation Trust (UHS) facility for diagnostic and research microscopy. The BIU houses microscopes capable of 2-, 3- and 4D imaging (from brightfield microscopy through to confocal, light sheet, time lapse, virtual scanning, µCT, SEM, TEM & serial block face SEM) using a range of imaging sources (light, x-ray and electron). We are the only joint NHS/University imaging facility in the...

Biometrology - measuring biological systems to support the development of new bioproducts and services

NPL, as the UK's National Measurement Institute, is the prime deliverer of the UK Measurement Strategy. NPL is a world-leading centre of excellence in developing and applying the most accurate measurement standards, science and technology available. For more than a century, NPL has developed and maintained the nation's primary measurement standards. These standards underpin an...