The biological mass spectrometry suite provides analytical expertise and practical support for academic (internal and external) and industrially funded research using high-end advanced analytical instrumentation. The facility has a range of liquid and gas chromatographs hyphenated with various mass spectrometers (LCMS and GCMS). Each instrument is dedicated to either proteomics (targeted, shotgun and non-labelled quantitation) or metabolomics (targeted/ untargeted metabolite profiling...

The Biomedical Imaging Unit is a joint University of Southampton (UoS)/ University Hospitals Southampton NHS Foundation Trust (UHS) facility for diagnostic and research microscopy. The BIU houses microscopes capable of 2-, 3- and 4D imaging (from brightfield microscopy through to confocal, light sheet, time lapse, virtual scanning, µCT, SEM, TEM & serial block face SEM) using a range of imaging sources (light, x-ray and electron). We are the only joint NHS/University imaging facility in the...

Our members in the Biomedical Sciences Research Institute (BMSRI) at Ulster conduct pioneering, strategically focused research into health and investigates the underlying causes, diagnosis, treatment and prevention of human diseases.We are also exploiting the remarkable opportunities made possible by recent molecular advances: revolutionary changes in biomedicine and biotechnology that will soon transform whole industries and economies, but which offer particular advantages in our field. We...

Biometrology - measuring biological systems to support the development of new bioproducts and services

NPL, as the UK's National Measurement Institute, is the prime deliverer of the UK Measurement Strategy. NPL is a world-leading centre of excellence in developing and applying the most accurate measurement standards, science and technology available. For more than a century, NPL has developed and maintained the nation's primary measurement standards. These standards underpin an...

The NMR facility provides research infrastructure and expertise primarily for projects related to biomacromolecules and their binding partners. Mostly supporting the various users from the Departments across the University, the facility is also open to external users from academia and industry. The majority of the work in the facility is done on a collaborative basis and support is adjusted according to the requirements of the users. The facility has three spectrometers that are operating at 800...

The Biophysical Analysis platform offers four techniques; Surface Plasmon Resonance (SPR) Isothermal Titration Calorimetry (ITC) Mass Photometry (MP) and Circular Dichroism Spectroscopy (CD).

SPR and ITC are complimentary techniques that can be used to study the binding of biomolecules. They can be used to identity interactions and obtain data on the affinity, kinetics, stoichiometry and thermodynamics of the binding interaction.

Mass Photometry enables the accurate mass determination of...

What it does: BioPilotsUK is a distributed infrastructure providing access to key hardware, skills and knowhow, for both industrial and academic R&D to aid innovation and de-risk the development of bio-based products and processes. Research Goals etc: • Provide simple-to-access responsive support to academia and businesses to accelerate innovative growth in the UK bioeconomy. • To assist UK industry realise potential investments in biobased research and innovation and bring new products to...