UK Biobank is a major national and international health resource, and a registered charity in its own right, with the aim of improving the prevention, diagnosis and treatment of a wide range of serious and life-threatening illnesses to including cancer, heart diseases, stroke, diabetes, arthritis, osteoporosis, eye disorders, depression and forms of dementia. UK Biobank recruited 500,000 people aged between 40-69 years in 2006-2010 from across the country to take part in this project. They...

The National Biosample Centre Established by the NIHR in 2014, and operated by UK Biocentre as a not-for-profit organisation, we provide world leading sample management and high capacity bioprocessing. We make extensive use of dedicated automation and software systems for consistent and high throughput sample processing and tracking delivering best value for UK medical research. Our mission is to be the centre of excellence for UK sample management and a key part of the UK science...

The UK Biochar Research Centre (UKBRC) undertakes disciplinary and interdisciplinary research on: (1) Biochar production and analysis of energy rich co-products; (2) The diverse potential applications of biochar; particularly as a beneficial soil amendment, as well as other uses; (3) The feasible development of Pyrolysis-Biochar systems and Life Cycle Assessments for sustainable resource management. The facility contains four major instruments for the pyrolysis and characterisation of biochar...

The biological mass spectrometry suite provides analytical expertise and practical support for academic (internal and external) and industrially funded research using high-end advanced analytical instrumentation. The facility has a range of liquid and gas chromatographs hyphenated with various mass spectrometers (LCMS and GCMS). Each instrument is dedicated to either proteomics (targeted, shotgun and non-labelled quantitation) or metabolomics (targeted/ untargeted metabolite profiling...

The Biomedical Imaging Unit is a joint University of Southampton (UoS)/ University Hospitals Southampton NHS Foundation Trust (UHS) facility for diagnostic and research microscopy. The BIU houses microscopes capable of 2-, 3- and 4D imaging (from brightfield microscopy through to confocal, light sheet, time lapse, virtual scanning, µCT, SEM, TEM & serial block face SEM) using a range of imaging sources (light, x-ray and electron). We are the only joint NHS/University imaging facility in the...

Opened in 2009, the BRC hIPSCs core facility was established to support the clinical applications of human pluripotent stem cells including disease modelling and regenerative medicine. Accordingly, the hIPSCs core Facility provides the following services: • Derivation of hIPSC lines for disease modelling: The core facility has successfully generated high-quality iPSCs from more than 500 patients. Upon request, the core facility can derive hIPSCs from dermal fibroblast cultures or peripheral...

Our members in the Biomedical Sciences Research Institute (BMSRI) at Ulster conduct pioneering, strategically focused research into health and investigates the underlying causes, diagnosis, treatment and prevention of human diseases.We are also exploiting the remarkable opportunities made possible by recent molecular advances: revolutionary changes in biomedicine and biotechnology that will soon transform whole industries and economies, but which offer particular advantages in our field. We...

Biometrology - measuring biological systems to support the development of new bioproducts and services

NPL, as the UK's National Measurement Institute, is the prime deliverer of the UK Measurement Strategy. NPL is a world-leading centre of excellence in developing and applying the most accurate measurement standards, science and technology available. For more than a century, NPL has developed and maintained the nation's primary measurement standards. These standards underpin an...

The NMR facility provides research infrastructure and expertise for structural biology projects. Primarily supporting in-house users, the facility can be accessed by external users from academia and industry. The majority of the work in the facility is done on a collaborative basis. Support is adjusted according to the requirements of the users.

At the John Innes Centre we have two biophysical analysis technologies; Surface Plasmon Resonance - which is a versatile, label-free system for detailed studies of biomolecular interactions in real time Isothermal Titration Calorimetry - which is the gold standard technique to probe biomolecular interactions in solution and is a thermodynamic technique that directly measures the heat released or absorbed during a biomolecular binding event Both Surface Plasmon Resonance and Isothermal Titration...